This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. Which diseases are killing people the most and what to do about it. But I think every once in a while, its good to make them a little uncomfortable and stretch them a little bit. A surgeon who developed metabolic syndrome himself despite the fact that he ate well and exercised often, Attia realized that our understanding of these important health issues may not actually be correct. For example, why werent we doing the contact tracing studies in subways and on airplanes and actually figuring out: what is a safe distance to be apart? Below this, it has no benefit, above this, its toxic. Part of the practice includes nutritional biochemistry, a field that deals with supplements. It turns out that our bodies perform a lot of glucose disposal when we sleep, so sleep is incredibly important for preventing glucose from building up in our bloodstreams. And I think most people do find a lot of benefit from it. I mean, this is not an unethical thing to do. It was about 10 things. CAUSE THE OBESITY EPIDEMIC IN THE UNITED STATES? I want to be able to hop over a three-foot fence. ATTIA: So a big part of our clumsy response to this is that it couldnt be centrally coordinated. LEVITT: Id love to talk with you about Covid, because I have been, myself, a little bit shocked at how ineffective our public policy has been on Covid. But there was a brutal concussion I had. Dr. Attia is medical doctor who focuses on the science behind living a longer, healthier life. . And so it might be that its the rigidity of thought that is really the biggest problem. Because for most people, the last 20 years, especially the last 10 years, are not great, both physically and cognitively. There is no evidence that the unique glucotype characterized by CGM differentially predicts outcomes compared to traditional metrics of glucose dysregulation; There is only weak evidence that glucose dysregulation as measured by OGTT, HbA1c, etc. Its the cognitive piece so how well does your brain work as you age? Have any hacks how to do? Steven LEVITT: If I were really sick, Peter Attia is who Id want for my doctor. He is the Co-founder and Chief Medical Officer of the fasting app Zero. In fact, Dr. Peter recommended to stop eating about three hours before bedtime. LEVITT: All right, so lets talk about your very unusual background. I hope you loved this episode as much as I did. Residency didnt seem very merit-based. What Happened To Peter Attia. I think they often get confounded. But it could put a slightly different interpretation on it. Last week, Peter Attia wrote a criticism of Game Changers, where he presented the argument (long repeated him) that nutritional epidemiology is fundamentally flawed. My Centenarian Olympics has 18 events in it. When we eat, our bodies naturally raise our temperature its just part of the digestion process. He attended Stanford University School of Medicine, where he received his M.D. ATTIA: What an obnoxious idiot I was. You can really imagine the matrix of studies that needs to be done, which says, O.K., what does transmission look like inside versus outside? And I remember once I was being interviewed and someone asked me: if you could be granted immortality or something, would you take it? Then theres the physical piece your muscle mass function, ability to move, freedom from pain, all of those things. Note this may include abusive, threatening, pornographic, offensive, misleading or libelous language. It gives me a greater respect for a sport that I once did that I didnt even have at the time. Its great to live until youre 90 or 100 years old, but if you spend the last 20 or 30 years in so much pain or with a neurodegenerative disease like Alzheimers, youre not really enjoying those last few decades. 3K? For all its successes, mainstream medicine has failed to make much progress against the diseases of aging that kill most people: heart disease, cancer, Alzheimers disease, and type 2 diabetes. And we do that a ton. So I dont really chew it that much anymore, just out of sheer laziness. Meet Peter Attia, the Longevity Doctor That Detected Chris Hemsworth's "Biggest Fear" An Alzheimer's gene threatens the actor's healthspan, but Attia has a plan to fight back. Autophagy is, as its name implies auto is self, phagy is eating so its when these cells eat themselves. And then, of course, this third piece, which is the emotional resilience and the ability to maintain a tolerance around distress. Dr. Peter Attia. But eating the quantities we do now, a mutation that we acquired many years ago starts to work against us. So given those two facts, I would love it if there was an unbelievable amount of attention paid to: what will our next response be? The problem was, it was the winter. We would like it such that, when you die, its really your first encounter with death of any form. Dr. Peter Attia. I actually find a fasting sleep to be some of the most amazing because Im watching this plummeting temperature, rising heart rate variability, falling heart rate, all of those really valuable things. Dr. Peter Attia. So you went to Stanford and got your medical degree there and then you did your residency at Johns Hopkins. So we evolved this way to instead break down fat, which even under the leanest times, you still had days, if not months worth of energy from, because fat is so energy-dense, and we could turn that fat into a molecule called a ketone. Those three effectively make up three quarters of deaths of people who dont smoke. Dr. Peter Attia. Aside from preventing chronic diseases like Type 2 diabetes, how can we extend our healthspans to become, as Dr. Peter put it, kick-ass 100-year-olds? to do just that, Dr. Peter structures his exercise around four main pillars: My training is very specific, but now it is fundamentally organized around four pillars: Stability, strength, mitochondrial or aerobic efficiency, and anaerobic performance. Dr. Peter Attia. But when you consume too much glucose, your body cant use it. Thanks, interesting.This is a lot of psyllium to swallow. Dr. Peter focuses on the applied science of longevity, the extension of human life, and overall well-being. What things are attributing to bad sleeping patterns. ATTIA: No, I think its the hardest job. And I actually do find this topic interesting. Apparently Peter and his buddy Gary Taubes just love themselves some crappy pseudoscience. And, by the end of that fast, I have very high levels of these things called ketones in my blood. [1] [2] He is also the first person to make the round-trip swim from Maui and Lanai. So the other thing we always want to be optimizing around is how much fiber can you get? I admire his dedication to becoming a kick-ass 100-year-old, and I only hope I can do the same! I lived in Boston. scan a couple days later. , a weekly, deep-dive podcast focusing on maximizing longevity by working on physical, cognitive, and emotional health. We won. It started very early. ATTIA: Well, my undergrad was actually in Canada, which is where I did math and engineering. Im involved in a coronavirus study now, that were trying to get off the ground, thats looking at the long term impact of immunity. Additionally, Dr. Peter is an advisor to and/or investor in the following companies: Virta Health, Hu Kitchen, Oura Health Oy, Magic Spoon Cereal, Inevitable Ventures, Salutoceuticals, Dexcom, and Supercast. And during all of this intentional exercise, Dr. Peter has one thing in mind: his Centenarian Olympics. Youll be able to read more about this in Dr. Peters book when it comes out, but for now, I can tell you that the Centenarian Olympics is a series of activities that Dr. Peter wants to be able to do when he turns 100. ATTIA: Yeah, but you have to remember, I mean, the N.I.H. He is an ultra-endurance athlete, compulsive self-experimenter, and one of the most fascinating human beings I know. Maybe it was partly the placebo effect of all your happy stories about it. I basically had the worst headache of my life for the next three months. And you would say, Peter, those seem really easy, and youd be right as a 37-year-old stud, but the point is most 60 year olds couldnt do them. Dr. Peter Attia. for Dr. Peters definition of greatness, so for now, Ill leave you with one final piece of wisdom: There are people out there who have so many genetic things working against them, that theyll be lucky to make it to 80. that was typically done by putting your finger in the air and looking at which way the wind blows. Comments deemed to be spam or solely promotional in nature will be deleted. Both of them are funded by the Arnold Foundation, with substantial ties to animal agriculture industry lobbying. Dr. Peter trained for five years at the, in general surgery, where he was the recipient of several prestigious awards, including Resident of the Year. Hes spent the last few years being mentored by the top medical scientists and now hosts. And so for six months, Ive been doing something that was probably a really bad idea as well. And I religiously do whatever you tell me to do. ATTIA: I dont know. Sign-up (free) to receive the5 Tactics in my Longevity Toolkitdelivered by email as a 5-day course. But the probability, Steve, that you or I may get the rest of our lives without another pandemic must be viewed as exceedingly small. And then after school, I would get home and then do another 90 minutes of work on the heavy bag, speed bag, double end bag in my basement, coupled with more anaerobic training. LEVITT: The set of things hes done to his body over time, in the spirit of self-experimentation, are mind-blowing. Today, we have more medical knowledge than ever before. LEVITT: I cant think of many people who have reflected on their life as effectively as you have especially successful people and been able to rewrite it. So my guess is, theres some measure around helping them become better thinkers. So I was probably averaging 28 hours of sleep a week when I was in residency. He is well . And then at lunch we would go to the University of Toronto I grew up in Toronto so wed go to University of Torontos weight room and do our really heavy lifting. I could basically, within two weeks, turn you into an almost-diabetic by sleep depriving you. Dr. Peter Attia. is incredibly risk averse. That was painful to watch. And it was at that point that I learned about this company called McKinsey that was like business school that you got paid for. After obtaining his medical degree from Stanford University, he was a surgeon at Johns Hopkins and worked at the National Cancer Institute. My practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life). We can be reached at radio@freakonomics.com. Taubes and his cofounder,. Its about exercising intentionally. Pacific Standard", "Blaming the Patient, Then Asking Forgiveness", "Silicon Valley Wants to Cash In on Fasting", "Attia P. TED: Is the Obesity Crisis Hiding a Bigger Problem? And I came across this Noam Chomsky documentary. into a difficult position, which is to make very incremental steps in science. And again fortunately, Olivias my oldest and shes 11. And senescent cells basically send out these really nasty inflammatory signals to other cells that basically age them. Dr. Peter is the perfect person to talk to about health and longevity, and Im excited to have him on The School of Greatness today! But I think there was a very similar insecurity. And then you have to have a third project, which is like 75 percent done. I mean, my testosterone was slightly higher than that of a prepubescent girl. And its unfortunate that it was typically packaged with an otherwise horrible set of molecules in cigarettes. Peter Attia is a Canadian-born doctor who focuses on the science of longevity. And you said, Well, Im allergic to sugar. And with a great deal of curiosity, she said, What happens to you when you eat sugar? And you looked at her completely deadpan. If you want bread, eat the bread that has no sugar. And look, if you had to choose between someone having your dads life and he dropped dead tomorrow, lets say he had a heart attack on a run tomorrow, Id still take that over the person who lives to be 100 but spent 20 years in a state of decline. Peter Attia, MD, is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. He is the host ofThe Drive, one of the most popular podcasts covering the topics of health and medicine. And then youd just be guaranteed to get N.S.F. So when you contrast living to 70 [and] spending 20 years in misery versus living to 75 with maybe two years in misery, it just doesnt even strike me as a trade-off. . If anything, I might even be more concerned with sugar, especially in its liquid form. on their work. Prior to that, in 1996, he received a Bachelor of Science degree in Mechanical Engineering and Applied Mathematics from Queen's University. I dont do such silly things anymore. ATTIA: I dont know if that exercise did, but yes, I think a lot of the training that I did did pay off, actually. Its not about exercising. Dr. Peter says there are four main ways to do it. Despite the fact that he exercised and followed a healthy diet, in 2009, Attia was overweight and had started developingmetabolic syndrome, putting him at risk for type 2 diabetes, heart disease and stroke. Peter Attia: "I Definitely Lost a Lot of IQ Points That Day" He's been an engineer, a surgeon, a management consultant, and even a boxer. So the former is one molecule of something called glucose and one of fructose bound together. The problem is that we may be living longer, but were living with chronic health conditions that significantly lower our quality of life. Born: 1973. ATTIA: I think without a step-function change in our technology and our understanding of science, it probably depends on how bad they are to begin with. And they mightve spent the last 20 of those years in an unbelievable state of misery. According to Tools of Titans, Attia takes 600 to 800 mg per day of magnesium, alternating between mag sulfate and mag oxide. Our lifespan is the amount of time we live, and it is steadily growing longer. By implication, it cannot be used to make nutrition recommendations. Lets watch this thing instead. And shes like, Who is this guy? And I said, Look, I dont agree with half the things this guy says, but he is categorically one of the smartest dudes ever. And theres no getting around that. Try playing chess with it, its so confident gives you a very detailed analysis why it's making a move and why your move was wrong, but tried to make illegal moves and doesn't I am responding to this post because: a) Peter's post made it into my message [] The four pillars of being a kick-ass 100-year-old. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease) while simultaneously improving healthspan (quality of life). And the more I learned, frankly, the less I agreed with him. It is the one thing that makes all three of those worse, and, in its most extreme state, its Type 2 diabetes. Dont just listen to people say stuff you agree with. ATTIA: So there were a lot of things that were really upsetting me at the time. And then probably have N.I.H. What type of a mask really matters? And its a finding that basically predicts early onset of cardiovascular disease, which shouldnt have been a surprise to me because the list of men in my family who have died of cardiovascular disease is pretty long. LEVITT: You have given a lot of advice already about nutrition and health. His unique spectrum of experience, relentless obsession over details, and ability to translate the cutting edge of science into something the rest of us can use is invaluable., Ive always been fascinated with medicine. That way, we can live lives that are both long and healthy! LEVITT: This is not a cheap study, I imagine. As an Amazon Associate, Freakonomics may earn commissions from qualifying purchases made through links on this site. But Im not the person thats actually going to do these studies. ATTIA: Yeah, I mean, most of these viruses are actually benign enough. Comments that harass other posters will be deleted. 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